Postexposure Prophylaxis of HIV

A checklist of recommendations on how to prevent HIV infection after exposure for medical professionals.

HIV Postexposure Prophylaxis (PEP) For Percutaneous Injuries
1
-HIV-Positive Class 1
2
Less Severe Exposure: Recommend basic 2-drug PEP
3
More Severe Exposure: Recommend expanded 3-drug PEP
4
-HIV-Positive Class 2
5
Less Severe & More Severe Exposure: Recommend expanded ≥3-drug PEP
6
-Source of Unknown HIV Status
7
Less Severe & More Severe Exposure: Usually no PEP; consider basic 2-drug PEP for source with HIV risk factors
8
-Unknown Source
9
Less Severe & More Severe Exposure: Usually no PEP; consider basic 2-drug PEP in setting where exposure to HIV-infected persons is likely
HIV Postexposure Prophylaxis (PEP) For Mucous Membrane Exposures And Nonintact Skin Exposures
1
-HIV-Positive Class 1
2
Small Volume: Consider basic 2-drug PEP
3
Large Volume: Recommend basic 2-drug PEP
4
-HIV-Positive Class 2
5
Small Volume: Recommend basic 2-drug PEP
6
Large Volume: Recommend expanded ≥3-drug PEP
7
-Source of Unknown HIV Status
8
Small Volume: Usually no PEP
9
Large Volume: Usually no PEP; consider basic 2-drug PEP for source with HIV risks
10
-Unknown Source
11
Small Volume: Usually no PEP
12
Large Volume: Usually no PEP; consider basic 2-drug PEP in setting where exposure to HIV-infected persons is likely
Created by Smith62. This checklist is public.
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